The purpose of this study is to determine whether implementation of an innovative STI prevention intervention design affects participants’ knowledge of sexually transmitted infections and sexual self-efficacy. The population this research focuses on is African-American adolescent girls. The participants included in this study are aged 13-19. This particular population is disproportionately infected by sexually transmitted diseases, so it is vital that intervention programs be tailored to fit their culture and gender-specific needs in order to achieve maximum results. However, current interventions for African-American girls could be improved. The researcher has designed an innovative STI prevention intervention that draws from current, best evidence interventions. The researcher has hypothesized that: (1) participants that complete the intervention will have increased STI knowledge; and, (2) upon completion of the intervention, participants will have greater sexual self-efficacy.