McNair Scholars Research Journal


DNA repair is a crucial part of organismal survival. The repair process is carried out by DNA polymerases and mismatch repair proteins. Things don’t always go as planned in DNA repair, and sometimes DNA repair is inaccurate. Inaccurate DNA repair can potentially lead to the loss of the genes important for cell division and replication. There has been much research into the efficiency of these DNA polymerases, yet there has been no thorough research into how the accuracy of repair is distributed among all of the different types of homologous recombination. The goal of this article is to review the literature on the accuracy of DNA repair during replication in Saccharomyces cerevisiae.