Date Approved


Degree Type

Open Access Thesis

Degree Name

Master of Science (MS)

Department or School

Health Sciences

Committee Member

Judith Brooks, PhD, Chair

Committee Member

George Liepa, PhD

Committee Member

Katherine L. Tucker, PhD


Background: Whole grains and their nutrient components have an important protective effect on the metabolic syndrome. Studies are needed to examine their bioactive components in relation to diet and the metabolic syndrome.

Objective: Our objective was to examine the associations between dietary intakes of whole grains and the metabolic syndrome.

Design: The study subjects were 1516 healthy men and women participating in the Baltimore Longitudinal Study of Aging. Dietary information was collected with 7-day food records, and estimates of whole grain intake were obtained from a newly developed database.

Results: A total of 17% (n = 251) of subjects met the definition for the metabolic syndrome. After adjustments for age, sex, and total energy, a modest inverse association was observed between whole-grain intake and the metabolic syndrome [odds ratio (OR): 0.90; 95% CI: 0.83, 0.97]; however, this was no longer statistically significant after adjustment for physical activity.

Conclusions: Although our study shows a modest inverse association between whole grains and the metabolic syndrome, this relationship was no longer statistically significant after controlling for other lifestyle factors.

Included in

Nutrition Commons