Date Approved


Degree Type

Open Access Thesis

Degree Name

Master of Science (MS)

Department or School


Committee Member

Gregg Wilmes, PhD,

Committee Member

Cory Emal, PhD

Committee Member

Timothy Friebe, PhD


Catalysts are reagents used to reduce the amount of energy that a reaction needs to execute, allowing it to proceed at a higher rate while not being consumed. The use of catalyst functionalized amphiphilic copolymer allows easier recovery of the catalyst at the end of the synthesis and allows for the reaction. In water, under appropriate conditions, the amphiphilic block copolymers will form micelles and allow the reaction to occur on the interior of the micelle. The synthesis of amphiphilic copolymer with a hydrophobic O-methacryloyl-trans-4- hydroxy-L-proline and methyl methacrylate end and a hydrophilic acrylic acid end was characterized. The polymer was tested as an asymmetric catalyst for an aldol reaction in aqueous conditions. The polymer was able to successfully stereoselectively catalyze the reaction with a preference for the anti-addition.