Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism

Authors/Creators

Daniel A. Lawrence, University of Michigan - Ann Arbor
Dudley Strickland, University of Maryland, Baltimore
Jacqueline Cale
Enming Joe Su, University of Michigan - Ann Arbor
Cory Emal, Eastern Michigan University
Mark Warnock, University of Michigan - Ann Arbor

Document Type

Patent

Date of Patent

6-24-2014

Abstract

The invention relates to plasminogen activator-I (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.

Original Assignee(s)

The Regents of the University of Michigan ; University of Maryland, Baltimore ; Eastern Michigan University

Comments

C. Emal is a faculty member in EMU's Department of Chemistry.

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Recommended Citation

Lawrence, D., A., Strickland D., Cale, J., Su, Enming Joe, Emal, C., & Warnock, M. (2014). Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism (U.S. Patent No. 8,759,327). U.S. Patent and Trademark Office.

Patent Number

US 8,759,327