Tracey Churay

Date Approved


Degree Type

Open Access Thesis

Degree Name

Master of Science (MS)

Department or School

Health Sciences

Committee Member

Irwin Martin

Committee Member

John Magenau


This thesis set out to examine whether the demographic diversity of participants in clinical trials involving allogeneic stem cell transplant recipients matched the diversity of the actual allogeneic recipient population overall. It is important that clinical trials study new therapies in a population that represents characteristics of the overall treatment population in order to gain accurate safety and efficacy data. The actual diversity of the allogeneic transplant population was determined using data reported to the Center for International Blood & Marrow Transplant Research (CIBMTR) registry. Then, a comprehensive literature review was conducted to identify the population of allogeneic transplant recipients who took part in clinical research. In comparing the two populations, it was determined that women are well-represented in allogeneic transplant trials, while non-white minorities remain underrepresented. These findings demonstrate that there is more work be done in order to ensure everyone has equal access to clinical trials.