Date Approved

2020

Degree Type

Open Access Thesis

Degree Name

Master of Science (MS)

Department or School

Health Sciences

Committee Member

Jean Rowan, MD, MS

Committee Member

Haley Neef, MD

Abstract

Pediatric patients with ulcerative colitis (UC) represent a high-risk population with severe disease that requires hospitalization. This study evaluates the impact of implementing an acute UC management protocol on 39 pediatric patients. After analysis, significant trends were shown for admitted pediatric patients post-protocol implementation, helping to coordinate multidisciplinary care sooner during a hospital stay. The patients were more likely to have a surgical consult, and the surgical consult was completed closer upon admission. The median length of hospital stay did not change, total parenteral nutrition use was increased, and oral steroids upon discharge were decreased. Anti-tumor necrosis factor alpha was given to more patients earlier upon admission, and the colectomy rate did not change but was more likely to be conducted sooner as an inpatient procedure. While further research with a larger patient population is needed, the benefits of an acute UC management protocol have been shown.

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